Highlights
- •Programs to prevent adverse effects of parental mental illness in children have shown benefits. Nevertheless, economic evaluations are scarce and methodologically challenging.
- •We provide an overview on the spectrum of adverse consequences of parental mental illness in children and society and give an orientation on how this knowledge may be translated into the design of an economic evaluation regarding perspective, study type, time horizon, and selection of costs and outcomes.
- •Economic evaluations of family-focused interventions when parents have a mental illness require careful design and possibly deviation from standard methods (eg, quality-adjusted life-years) to avoid decisions based on misleading cost-effectiveness results.
Abstract
Objectives
Methods
Results
Conclusions
Keywords
Introduction
- Nicholson J.
- Biebel K.
- Katz-Leavy J.
- Williams V.
- Williams
Methods
Impact Inventory
Strohmaier C, Hölzle L. The economic and societal dimension of parental mental illness. Austrian Institute for Health Technology Assessment GmbH. https://eprints.aihta.at/1351/1/HTA-Projektbericht_Nr.142.pdf. Accessed March 25, 2022.
Data Sources
- Lindsay G.
- Strand S.
- Davis H.
Category | Definition |
---|---|
Population | Children or adolescents of parents with a mental illness aged ≥ 4 years and their parents Mental illnesses include all mental and behavioral disorders (F00-F99), for example, affective disorders, schizophrenia, and psychosis, with or without substance misuse |
Intervention/comparator | Not applicable |
Outcomes | All types of adverse consequences (health and nonhealth) from parental mental illness for children (short-term and long-term) |
Study design(s) | Empirical studies measuring adverse child outcomes, no restriction on study design (eg, population-based cohort studies, cross-sectional studies, case-control studies, and national surveys) |
Language | English or German |
Type of publication | Journal articles and research reports |
Search period | 2010 to May 2021 |

Data Analysis
Results

Individual Mental and Physical Health Impacts
Short-term health impact
- Lindsay G.
- Strand S.
- Davis H.
Long-term health impact
Individual Impact on Social Functioning
- Lindsay G.
- Strand S.
- Davis H.
Individual Socioeconomic Impact
Societal Impact
Economic Consequences
Private costs for individuals and families
Public sector costs at the societal level
Discussion
Strohmaier C, Hölzle L. The economic and societal dimension of parental mental illness. Austrian Institute for Health Technology Assessment GmbH. https://eprints.aihta.at/1351/1/HTA-Projektbericht_Nr.142.pdf. Accessed March 25, 2022.
Gardner F, Leijten P, Mann J, et al. Could scale-up of parenting programmes improve child disruptive behaviour and reduce social inequalities? Using individual participant data meta-analysis to establish for whom programmes are effective and cost-effective. NIHR Journals Library, King’s College London. https://kclpure.kcl.ac.uk/portal/en/publications/could-scaleup-of-parenting-programmes-improve-child-disruptive-behaviour-and-reduce-social-inequalities(e0c898e4-d53d-4d98-b6bd-606af1480f01)/export.html. Accessed May 14, 2022.
Weatherly H, Faria R, Sculpher MJ, et al. Scoping review on social care economic evaluation methods. Centre for Health Economics. https://eprints.whiterose.ac.uk/135405/1/CHERP150_social_care_evaluation_methods.pdf. Accessed August 22, 2022.
Gardner F, Leijten P, Mann J, et al. Could scale-up of parenting programmes improve child disruptive behaviour and reduce social inequalities? Using individual participant data meta-analysis to establish for whom programmes are effective and cost-effective. NIHR Journals Library, King’s College London. https://kclpure.kcl.ac.uk/portal/en/publications/could-scaleup-of-parenting-programmes-improve-child-disruptive-behaviour-and-reduce-social-inequalities(e0c898e4-d53d-4d98-b6bd-606af1480f01)/export.html. Accessed May 14, 2022.
Weatherly H, Faria R, Sculpher MJ, et al. Scoping review on social care economic evaluation methods. Centre for Health Economics. https://eprints.whiterose.ac.uk/135405/1/CHERP150_social_care_evaluation_methods.pdf. Accessed August 22, 2022.
Gardner F, Leijten P, Mann J, et al. Could scale-up of parenting programmes improve child disruptive behaviour and reduce social inequalities? Using individual participant data meta-analysis to establish for whom programmes are effective and cost-effective. NIHR Journals Library, King’s College London. https://kclpure.kcl.ac.uk/portal/en/publications/could-scaleup-of-parenting-programmes-improve-child-disruptive-behaviour-and-reduce-social-inequalities(e0c898e4-d53d-4d98-b6bd-606af1480f01)/export.html. Accessed May 14, 2022.
Guidelines for the economic evaluation of health technologies: Canada, 4th edition. Canadian Agency for Drugs and Technologies in Health. https://www.cadth.ca/sites/default/files/pdf/guidelines_for_the_economic_evaluation_of_health_technologies_canada_4th_ed.pdf. Accessed August 22, 2022.
Gardner F, Leijten P, Mann J, et al. Could scale-up of parenting programmes improve child disruptive behaviour and reduce social inequalities? Using individual participant data meta-analysis to establish for whom programmes are effective and cost-effective. NIHR Journals Library, King’s College London. https://kclpure.kcl.ac.uk/portal/en/publications/could-scaleup-of-parenting-programmes-improve-child-disruptive-behaviour-and-reduce-social-inequalities(e0c898e4-d53d-4d98-b6bd-606af1480f01)/export.html. Accessed May 14, 2022.
Knapp M, McDaid D, Parsonage M. Mental health promotion and mental illness prevention: the economic case. Department of Health. https://eprints.lse.ac.uk/39300/1/Mental_health_promotion_and_mental_illness_prevention%28author%29.pdf. Accessed August 22, 2022.
Gardner F, Leijten P, Mann J, et al. Could scale-up of parenting programmes improve child disruptive behaviour and reduce social inequalities? Using individual participant data meta-analysis to establish for whom programmes are effective and cost-effective. NIHR Journals Library, King’s College London. https://kclpure.kcl.ac.uk/portal/en/publications/could-scaleup-of-parenting-programmes-improve-child-disruptive-behaviour-and-reduce-social-inequalities(e0c898e4-d53d-4d98-b6bd-606af1480f01)/export.html. Accessed May 14, 2022.
Conclusions
Article and Author Information
Acknowledgments
Supplemental Material
References
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