P28 Impact of COVID-19 on Mental Health in Young Adults in the United States


      To assess the impact of COVID-19 pandemic on mental health in young adults in the US.


      Three waves of online surveys were designed to capture mental health status in the US (EuroQol grant: 84-2020RA): Wave1 (Apr 1st – May 6th, 2020 (n=2,734)), Wave2 (July 4th – Sept 4th, 2020 (n=2,454)), and Wave3 (Jan 10th - Mar 15th, 2021 (n=2,252)) using the EQ-5D-5L to evaluate respondent’s health-related quality-of-life (HRQoL) and the Patient Health Questionnaire (PHQ-4) to assess anxiety and depression. The EQ-5D-5L utility, VAS scores and 5 domains were stratified by age, gender, and race/ethnicity. Binary Logistic regressions were used to estimate the associations between anxiety/depression and various covariates. Chi-square tests were conducted for significant differences in mental health outcomes between age groups.


      Most participants were white (68.7%) non-Hispanic (89 %). On average, participants were 42 (±13) years old, 47% being female. In all 3 waves, self-reported anxiety and depression were significantly higher in young adults (18-34) compared with older adults (35+) (p<0.01). Anxiety scores were 42%, 53%, and 33% in waves 1-3 respectively for young adults, whereas 33%, 40%, and 22% were reported by adults 35-64 and 19%, 20%, and 12% were reported by adults 65+. Similar trends were observed for depression, with younger adults reporting 39%, 54% and 35%, compared with 27%, 38% and 22% for those aged 35-64 years and 14.5%, 16% and 14.85% for 65+. EQ-5D-5L utility in waves 1-3 were 0.82, 0.75, and 0.82 (P<0.01) and 74.7, 78.7, and 76.4 for EQ-VAS (P<0.01). Age and employment status were significant predictors for anxiety and depression outcomes.


      Mental health deterioration during COVID-19 was pronounced among young adults for all waves, especially in wave2. Findings suggest although people adapt over time, the US was ill-prepared for a mental health crisis, especially among young adults.