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Understanding Differences Among Erectile Dysfunction Patients Globally

      OBJECTIVES

      Erectile dysfunction (ED) is a common sexual problem in men, although under-reporting of ED is widespread. This analysis seeks to explore the prevalence of the condition across select geographies and to compare the profile of sufferers among men identifying with an ED problem.

      METHODS

      Data from 94,711 men interviewed in the US, EU (UK, France, Germany, Italy, Spain), Japan (JP), China (CH), Brazil (BR), and Russia (RU) National Health and Wellness Surveys, a cross-sectional Internet or CAWI-based survey representative of the adult population, conducted in 2011 or 2012. Data were weighted based on sex and age for each region. Men were classified as having ED if in the past six months, they had difficulty achieving/maintaining an erection. Health-related quality of life (HRQoL) was assessed with the SF-12v2, and activity impairment was measured with the Work Productivity and Activity Impairment questionnaire (WPAI). Comparisons between patient groups were made with chi-square tests for categorical variables and ANOVA for continuous variables.

      RESULTS

      Prevalence of ED differs significantly across geographies, with Japan having the highest percentage (42.6%, 21.7 M) followed by China (34.7%, 87.8 M) and US (33.7%, 37.6 M), and Brazil having the lowest (14.9%, 10.0 M) (p<0.05). In the established markets (US, EU, Japan) ED sufferers are significantly older (mean ages 51, 57 and 52, respectively) than in emerging markets (CH, BR, RU) (mean ages 45, 44 and 46) (p<0.05). Men with ED in Russia had significantly lower PCS (45.5) and MCS (42.3) QoL scores compared to all other regions (p<0.05). Men with ED in China reported the greatest degree of work productivity loss (34% vs. ~20 – 25%, p<0.05) and activity impairment (32% vs. 19 – 30%, p<0.05).

      CONCLUSIONS

      Cross-regional comparisons of Erectile Dysfunction can provide insights to the magnitude of the problem and assess disease burden among these sufferers.