Research poster presentation - session II Disease-specific studies: Systemic disorders/conditions – patient-reported outcomes & patient preference study| Volume 15, ISSUE 4, PA107, June 01, 2012

PSY46 Burden of Disease in Patients With Diagnosed Psoriasis in Brazil: Results From 2011 National Health and Wellness Survey (NHWS)


      Currently in Brazil's public healthcare, patients with psoriasis who fail the available treatment options (phototherapy, methotrexate, acitretin and cyclosporin) due to any cause, are experiencing a medical unmet need. This study is aimed to assess comorbidity, quality of life (QoL), work/productivity loss (WPL), and medical resource utilization in patients diagnosed with psoriasis (PdwP) in Brazil.


      A total of 12,000 individuals' (age 18+) self-reported data were collected from 2011 National Health and Wellness Survey (NHWS) in Brazil, a cross-sectional representative sample of the adult population. QoL was measured by the physical component score (PCS) and mental component score (MCS) of the Short Form-12 (SF-12). WPL was measured by the validated Work Productivity and Activity Impairment instrument. Medical resource utilization was measured by health care provider utilization, emergency room visits and hospitalization in the past 6 months.


      Of the 12,000 respondents, 205 (1.3%) were patients diagnosed with psoriasis (PdwP) (53.0% women). Mean age was 40.2. Higher percentage of co-morbidities was found among PdwP compared to patients not diagnosed with psoriasis (PndP): headache (71% vs. 54%), sleep difficulties (50% vs.24%), anxiety (50% vs.33%), insomnia (46% vs.22%), pain (42% vs.23%), skin allergies (40% vs.17%), migraine (40%vs.20%), Heartburn (38% vs.23%) hay fever (37% vs.15%), nasal allergies (33% vs.21%), depression (33% vs.16%), rhinitis (32%vs.11%), high blood pressure (29% vs.16%), gingivitis (22%vs.6%), nail fungus (20%vs.7% ), dry eye (20% vs.5%), anemia (19% vs.6%), diabetes type 1 or 2 (19% vs.4%). PdwP had a lower mean PCS (45.8 vs. 49.7) and MCS (42.3 vs.47.0), more visiting health practitioners (87.0% vs.76.0%), emergency room visits (36.0%vs.22.0%), and hospitalizations for a medical condition (21.0% vs.10.0%) over the past 6 months compared to the PndP group. Furthermore, PdwP reported higher presenteeism (30.4% vs.14.8%), work productivity loss (34.0% vs 18.9%) and activity impairment (36.5% vs.20.9%) compared to the PndP group. All mentioned differences were statistically significant at p<0.05.


      From Brazilian NHWS results, PdwP suffer from impairment in QoL, WPL, and more co-morbidities.